Ambiguities arising from interrelationships between parameters

Ambiguities arising from interrelationships between parameters [Pg.172]

The best course to take when investigating correlations such as the Taft-Pavelich or the hydrophobic correlations is to examine closely the correspondence between model and reaction in hand. For example a strict dependence on in biological interaction could mean that the process mirrors the simple ester hydrolysis reaction in its steric requirements or that an identical steric requirement exists but which arises from a different mechanism such as entry of the substrate through a finite shaped cleft. [Pg.172]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...