Alternaria mali

The toxins of many members of the fungal genus Al-ternaria produce phytotoxins of these, many [such as AM-toxin I (18)] are peptides. The fungal pathogen Alternaria mali on apples produce necrotic lesions on the leaves, shoots, and fruits of susceptible cultivars (Natori et al, 1981). Alternaria kikuchiana, which causes black spot disease on the Japanese pear (Pyrus serotina) produces phytotoxins which are based on A -acetylphenylalanine and a Cio fatty acid (Harbome, 1986). 

Shimohigashi and coworkers described syntheses in the field of the Alternaria Mali toxins and related cyclodepsipeptides 452,453,454,454A, 455). For mass spectroscopy studies on these compounds see ref. 456). 

Okuno, T., Y. Ishita, K. Sawai, and T. Matsumoto Characterisation of Alter-nariolide, a Host-specific Toxin Produced By Alternaria Mali. Chemistry Letters 1974, 635. 

Ueno, T., T. Nakashima, Y. Hayashi, and H. Fukami Isolation and Structure of AM-Toxin III, a Host-specific Phytotoxic Metabolite Produced by Alternaria Mali. Agric. Biol. Chem. 39, 1115, 2081 (1975). 

Ueno, T., T. Nakashima, M. Uemoto, H. Fukami, S. Lee, and N. Izumiya Mass Spectrometry of Alternaria Mali Toxins and Related Cyclodepsipeptides. Biomed. Mass Spectrom. 1977, 134. 

Isol. from Alternaria tenuis and A. mali and Stemphylium botryosum. Phototoxin. Active against gram-positive bacteria. Orange cryst. solid. Mp 245-250° (300° dec.). [a]j3 -h636° (c, 0.001 in CHCI3). 

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