Alstonia lanceolifera

Deplancheine (7) was isolated first from the stem and bark of Alstonia deplanchei van Heurck and Muell. Arg. by Husson et al. (14). The structure of this novel type of alkaloid has been established from spectral evidence the trans annellation of rings C and D is supported by the presence of characteristic Bohlmann bands in the IR spectrum and also by the chemical shift of the C-3 proton below 3.7 ppm. The ethylidene side chain was also indicated by the H-NMR spectrum [8 1.52 (3H, d, J =6 Hz), 5.30 (1H, q, J = 6 Hz)] and its E configuration was confirmed by regio- and stereospecific total synthesis (14). 10-Methoxydeplancheine (8) has been found in the leaves of Alstonia lanceolifera... 

Details have been given of the isolation73c d of lanciferine and of ten other alkaloids from the leaves and twigs of Alstonia lanceolifera S. Moore in the last communication73 this plant is described as A. boulindaensis Boiteau. 

Sarpagine-Ajmaline-Picraline Group. (+)-Quebrachidine (142) is one of the minor alkaloids of the root bark of Cabucala striolata, and of the stem and root bark of C. torulosa, which also contains (-)-vincamajine (143). O-Trimethoxy-cinnamoylvincamajine (144), a known alkaloid, and six new vincamajine derivatives, have been extracted from the aerial parts of Alstonia lanceolifera. Three of the new alkaloids are 10-methoxy-3,4,5-trimethoxycinnamoylvincamajine (145), 10-hydroxy-3,4,5-trimethoxycinnamoylvincamajine (146), and 10-methoxyvinca-majine (147) the other three alkaloids are suspected to be the trimethoxybenzoyl... 

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