Alpha Carbon Chemistry Enols and Enolates

Fill in the blanks below. To verify that your answers are correct, look in your textbook at the end of Chapter 22. Each of the sentences below appears verbatim in the section entitled Review of Concepts and Vocabulary. 

In the presence of catalytic acid or base, a ketone wiU exist in equihbiium with an equihbiium will significantly favor the.  

When treated with a strong base, the a position of a ketone is deprotonated to give an.  

When an aldehyde is treated with sodium hydroxide, an aldol addition reaction occurs, and the product is a 

For most simple aldehydes, the position of equihbrium favors the aldol product. For most ketones, the reverse process, called a -aldol reaction is favored. 

---

Introduction to Alpha Carbon Chemistry Enols and Enolates... 

The stereoselective formation of quaternary stereogenic carbons remains both a challenging and important area of investigation. There have been numerous pathways to synthesize the carbon centers among these attempts, enolate alkylation represents one synthetic strategy. The alkylation of the alpha carbon of a carbonyl remains one of the most fundamental reactions in organic chemistry. However, with this important reaction and the vast number of studies conducted on the generation of and substitution of the enolate, it stiU has a number of inherent limitations. ... 

---