Allylic thiocarbamidates

Bromocyclization of allylic thiocarbamidates. Allylic thiocarbamidates (1), prepared as shown, on treatment with this reagent cyclize to bromo carbamates (2). This... 

THIOCARBAMIDE (62-56-6) Aqueous solution is a base. Violent reaction with acrolein, strong acids. Incompatible with acrylaldehyde, hydrogen peroxide, metal salts. Aqueous solution incompatible with organic anhydrides, acrylates, alcohols, aldehydes, alkylene oxides, substituted allyls, cresols, caprolactam solution, epichlorohydrin, ethylene dichloride, glycols, hydrogen peroxide, isocyanates, ketones, mtdeic anhydride, nitrates, nitromethane, phenols, vinyl acetate. 

The thiocarbamides with an aryl fragment at one nitrogen atom and -allylic and thietanyl fragments at the other have the highest activity with cumyl hydroperoxide, and among these compounds, A[-(o-methyl-phenyl)-A[ -allylthiocarbamide, has the highest stoichiometric coefficient (v) and markedly differs in its activity. 

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