Allergic rhinitis corticosteroid inhalation

Fluticasone is a potent corticosteroid that is available as a nasal spray indicated in allergic rhinitis (hay fever) and as an inhaler used in asthma. 

Bennett ML, Fountain JM, McCarty MA, Sherertz EF. Contact allergy to corticosteroids in patients using inhaled or intranasal corticosteroids for allergic rhinitis or asthma. Am J Contact Dermat 2001 12(4) 193-6. 

HPI KG is a 39-year-old woman with asthma on fluticasone and albuterol complaining of SOB associated with exercise. Three months ago she started an aerobic exercise program that has been hampered by chest tightness and SOB shortly after she begins running. She admits to poor compliance with her corticosteroid inhaler and requests an oral medication to control her asthma symptoms. Her PMH is significant for mild, persistent asthma for 35 years and allergic rhinitis. Her medications include fluticasone and albuterol inhalers and fexofenadine. Pulmonary function tests (PFTs) reveal her forced expiratory volume in the first second (FEV,) = 89% of predicted. 

Indications Allergic rhinitis, Asthma Category Corticosteroid, inhaled Half-life N/A... 

Budesonide is a corticosteroid/flucocorticoid/intranasal steroid. It exhibits a wide range of inhibitory activities against multiple cell types and mediators involved in aller-gic-mediated inflammation. Its indications are Intranasal management of seasonal and perennial allergic rhinitis symptoms in adults and children oral inhalation for the maintenance treatment of asthma as prophylactic therapy in adults and children and for patients requiring oral corticosteroid therapy for asthma inhalation suspension maintenance treatment of asthma and prophylactic therapy in children 12 months to 8 years of age oral capsule Crohn s disease. 

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