Alleigic reactions

This drug is indicated for infections of skin and nails due to dermatophytes or Candida species and vulvovaginal infections due to Candida species. Miconazole is used orally for prophylactic purposes in patients who have been treated with cytostatics or immunosuppressants, in particular, to prevent candidosis of the mouth and digestive tract. Side effects include possible nausea during oral treatment. Miconazole tablets may increase the anticoagulant effect of coumarin derivatives. Topical treatment with cream or powder is well tolerated. Local irritation and alleigic reactions of the skin and mucosa occur only rarely. 

Histamine. Histamiae [51 -45-6] (200) is an inflammatory autacoid iavolved ia alleigic and anaphylactic reactions (3,39,59) (see... 

The adverse effects include digestive disturbances, neurological symptoms, and manifestations of alleigic responses. As many as half of the patients taking it are incapacitated by some of these adverse reactions for several hours. Whether these symptoms are caused by hypersensitivity to the drug, the parasite, or by a manifestation of the disease is not known. Overall, effects are dose-related and transient. 

Type rv reactions to CSs are mainly diagnosed by patch testing. Tixocortolpivalate, budesonide, and hydrocortisone 17-buyrate are the principal drugs employed for testing. A combination of tixocortol pivalate and budesonide detects over 91.3 % of CS-alleigic patients. 

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