Alkaloids genes

HUANG, F.-C., KUTCHAN, T.M., Distribution of morphinan and benzo[c]phenanthridine alkaloid gene transcript accumulation in Papaver somniferum, Phytochemistry, 2000,53, 555-564. 

HaarmannT The ergot alkaloid gene cluster in Clavicepspurpurea. Extension of the cluster sequence and intra species evolution. Phytochemistry 66 1312— 1320, 2005. 

Tudzynski, P., Hotter, K., Correia, T., Arntz, C., Grammel, N. and Keller, U. 1999. Evidence for an ergot alkaloid gene cluster in Claviceps purpurea. Molecular and General Genetics, 261 133-141. 

Haarmann, T., Machado, C., Lubbe, Y., Correia, T., Schardl, C. L., Panaccione, D. G. and Tudzynski, P. 2005. The ergot alkaloid gene cluster in Clavicepspurpure Extension of the cluster sequence and intra species evolution. Phytochemistry, 66(11) 1312-1320. 

Keywords alkaloid biosynthesis alkaloid genes nicotine tropane alkaloids pyrrolizidine alkaloids benzylisoquinoline alkaloids monoterpene indole alkaloids ergot alkaloids acridone alkaloids purine alkaloids taxol betalains... 

Other Genes Hypothesized from C. purpurea Ergot Alkaloid Gene Cluster... 

P. B. F. Ouwerkerk, Regulation of terpenoi indole alkaloid genes from Catharanthus roseus. Ph.D. Thesis, University of Leiden, 1997. 

Known and Predicted Genes in the Ergot Alkaloid Gene Cluster of Clavicepspurpurea Strain PI. 

As depicted in Fig. 8.9 [5], plant alkaloid genes can be functionally expressed in microorganisms to produce either single biotransformation steps or short biosynthetic pathways. 

Lorenz N, Haarmann T, Pazoutova S, Jung M, Tudzynski P (2009) The ergot alkaloid gene cluster functional analyses and evolutionary aspects. Phytochemistry 70 1822-1932... 

Only if alkaloid genes are on the expected chromosomes. There are few (only 1 ). 

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