Algorithm-based Methods for the Discovery of Novel Multicomponent Reactions

Algorithm-based Methods for the Discovery of Novel Multicomponent Reactions 

Despite this interest, new reaction types in organic chemistry have been more usually found by chance than by rational design or logical consideration. In this chapter we emphasize that, although they are rarely used, there are both rational and, in particular, algorithm-based methods to discover novel multicomponent reactions. 

To begin with, it might be useful to define in general what a new reaction is. There are several methods available that are used to classify chemical reactions. 

Multicomponent Reactions. Edited by Jieping Zhu, Hugues Bienayme Copyright 2005 WILEY-VCH Veriag GmbH Co. KGaA, Weinheim ISBN 3-527-30806-7 

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