Alemtuzumab infusion reaction

Alemtuzumab Infusion-reactions fever, chills, nausea, vomiting rash Antiviral and PCP prophylaxis should be initiated... [Pg.1420]

Watch for infusion reactions with rituximab and alemtuzumab. Premedicate with acetaminophen and diphenhydramine to prevent these reactions. [Pg.1424]

Alemtuzumab CD52 B-cell chronic lymphocytic leukemia Infections, hematologic toxicity, infusion reactions, hypersensitivity... [Pg.455]

Immunologic Serious infusion reactions occurred in 1.4% of patients with multiple sclerosis treated with alemtuzumab [138. ... [Pg.784]

Alemtuzumab has been associated with significant infusion-related reactions (almost 90% of patients will experience fever and rigors during the infusion) and premedication is recommended. In addition, patients treated with this agent may become profoundly immunocompromised and are at... [Pg.156]

Alemtuzumab CD52 Normal and malignant B-lymphocytes, T cells, NK cells, monocytes, macrophages, platelets (not hematopoietic stem cells) Chronic lymphocytic leukemia Hypersensitivity and infusion related reactions, profound immunosuppression... [Pg.156]

Nervous system Infusion-related headache affected more than 50% of treated individuals in a cohort of patients with multiple sclerosis [138 ]. Anxiety, syncope, vertigo, dizziness, tremor, paresthesia, and hypesthe-sia are common undesirable reactions during treatment or within 30 days after the completion of treatment with alemtuzumab. Guil-lain-Barre syndrome and its chronic form, chronic inflammatory demyelinating polyradiculoneuropathy, have also been reported. [Pg.784]

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