Alcohols Dess-Martin

Popular oxidation reactions of peptide alcohols such as the Parikh-Doering or Dess-Martin in addition to older oxidation reactions such as Collins, pyridinium chlorochromate, or Swern oxidation afford racemization free productsJ9121415 37-39 Oxidations using pyridinium dichromate results in racemization and low yields of product.[l3 Oxidation reactions have also been utilized in semisynthetic pathways of peptide aldehydes (1) peptide aldehydes are obtained through the enzymatic acylation of a peptide ester to an amino alcohol with subsequent oxidation of the peptide alcohol to afford the aldehyde, and (2) peptide aldehydes can also be obtained by direct enzymatic oxidation of the peptide alcohol by alcohol de-hydrogenaseJ40 41 ... 

Ellis DA, JW Martin, AO De Silva, SA Mabury, MD Hurley, MPS Andersen, TJ Wallington (2004) Degradation of fluorotelomer alcohols a likely atmospheric source of perfluorinated carboxylic acids. Environ Sci Technol 38 3316-3321. 

Noel X, Paternot J, Van der Linden M, Sferrazza R, Yerhas M, Hanak C, Kornreich C, Martin P, De Mol J, Pelc I and Verbanck P (2001). Correlation between inhibition, working memory, and delimited frontal area blood flow measured by the 99MTc-Bicisate SPECT in alcohol-dependent patients. Alcohol and Alcoholism, 36, 556-563. 

Perez de los Cobos, J., S. Martin, A. Etcheberrigaray, J. Trujols, et al, A controlled trial of daily versus thrice-weekly buprenorphine administration for the treatment of opioid dependence, Drug Alcohol Depend., 59(3), 223-233, 2000. 

Martin, J. W., Mabury, S. A., O Brien, P. J. Metabolic products and pathways of fluorotelomer alcohols in isolated rat hepatoc)des. Chenr Biol. Interac., 155 165-180 (2005). 

De Munari, S., Frigerio, M., Santagostino, M. Hypervalent Iodine Oxidants Structure and Kinetics of the Reactive Intermediates in the Oxidation of Alcohols and 1,2-Diols by o-lodoxybenzoic Acid and Dess-Martin Periodinane. A Comparative 1H-NMR Study. J. Org. Chem. 1996, 61, 9272-9279. 

Moreno Martin, F. 1934. Influencia del alcohol metilico en la dosificacidn de alcoholes superiores en agardientea y licores. Congr. intern, quim, pura apl. 9(VI), 272-273. 

Ellis, D.A., J.W. Martin, A.O. De SUva, S.A. Mabury, M.D. Hurley, M.P.S. Andersen, and T.J. Wallington (2004), Degradation of Uuorotelomer alcohols A Ukely atmospheric source of perfluorinated carboxyUc acids. Environ. Sci. Technol, 38, 3316-3321. 

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