Alcohols chlorotris rhodium

The Step 1 product was stirred at 125°C in n-butyl acetate with /t-toluenesulfonic acid, then cooled, filtered, and washed with water. The mixture was then treated with water, ethyl alcohol, chlorotris(triphenylphosphine)rhodium, degassed, and heated for 3-5 hours at 75°C. The racemic acid was extracted with 2M NaOH, then washed with butyl acetate. It was then treated with methyl alcohol followed by the slow addition of 2 M HC1 and the product isolated by filtration. The material was used directly without further purification. 

Braun reaction, 0-73). In a similar reaction, treatment of N-alkyl-substituted amides with chlorotris(triphenylphosphine)rhodium RhCl(PPh3)3 or certain other catalysts give nitriles and the corresponding alcohols.419... 

Enantiomerically pure carboxylic acids are routinely obtained from N-acylsultams by Hydrogen Peroxide assisted saponification with Lithium Hydroxide in aqueous THF. 4 Alternatively, transesterification can be effected under neutral conditions in allyl alcohol containing Titanium Tetraisopropoxide, giving the corresponding allyl esters which can be isomerized/hydrolyzed with Wilkinson s catalyst (Chlorotris(triphenylphosphine)rhodium(I)) in Et0H-H20. This provides a convenient route to carboxylic acids containing base-sensitive functionality. Primary alcohols are obtained by treatment with L-Selectride (Lithium Tri-s-butylborohydride) in THF at ambient temperature. ... 

The synthesis of highly substituted /Sy-unsaturated ketones has been accomplished by reaction of allylmagnesium halides with 4,4-dimethyl-2-oxazolines. In the presence of a catalytic amount of chlorotris(triphenylphosphine)-rhodium(l), acyl chlorides and allyl tri-n-butyltin give the corresponding alkyl allyl ketone. A simple regiospecific synthesis of allyl ketones from allyl alcohols (Scheme 62) has been reported. ... 

It has been known for some years that the group VIII metals and metal salts catalyze the dehydrogenative solvolysis of hydrosilanes with amines, alcohols and carboxyhc acids [69]. Studies on the scope of these processes and the mechanistic investigations were limited to the use of monohydrosilanes. Recently, it has been found that chlorotris(triphenylphosphine)rhodium(I) (7) is exceedingly effective for the selective alcoholysis of hydrosilanes including polyhydrosilanes [33, 70]. 

Chlorotris(triphenylphosphine)rhodium(l) Alkoxysilanes from alcohols and silanes... 

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