Alcohol analogues

Scheme 3.16 P-Amino thiol ligand based on bicycle[2.2.1] ring system and its P-amino alcohol analogue for additions of ZnEt2 to aldehydes.

DL-Panthenol occurs as a white to creamy white, crystalline powder. It is a racemic mixture of the dextrorotatory (active) and levorotatory (inactive) isomers of panthenol, the alcohol analogue of pantothenic acid. It is freely soluble in water, in alcohol, and in propylene glycol. It is soluble in chloroform and in ether, and is slightly soluble in glycerin. Its solutions are neutral or alkaline to litmus. 

Claisen Rearrangements in Derivatives of Furfuryl Alcohol Analogues... 

Panthenol, USP. Panthenol, the racemic alcohol analogue of pantothenic acid, exhibits both qualitatively and quantitatively the vitamin activity of pantothenic acid. It is considerably more stable than pantothenic acid in solutions with pH values of 3 to 5 but of about equal. stability at pH 6 to 8. It appears to be absorbed more readily from the gut. paniculorly in the presence of food-... 

The utility of recyclable alumina as a viable support surface for deacylation reactions is described by Varma and his colleagues [83] wherein the orthogonal deprotection of alcohols is possible under solvent-free conditions on a neutral alumina surface using MW irradiation (Scheme 2.2-23). Interestingly, chemoselectivity between alcoholic and phenolic groups in the same molecule has been achieved simply by varying the reaction time phenolic acetates are deacetylated faster than alcoholic analogues. 

The latter compound is the amino alcohol analogue of the diamine (S)-2-(anilinomethyl)pyrrolidine (Scheme 3.1, Section 3.2.1). Not surprisingly, pro-linol has also been used to prepare bicyclic P-stereogenic oxazaphospholidines and derivatives thereof. As anticipated, their preparative methods are the same as those described in the preceding sections (Scheme 3.21). 

---