Albumin, trapped

The first really successful artificial material used in the manufacture of synthetic blood vessels was Dacron , a polyester fiber made from polyethylene terephthalate (PET). The material is woven or knitted into thin tubes with dimensions similar to those of a natural blood vessel. The tubes are then treated with coagulated blood or with albumin, an important blood protein, to block the tiny holes in the fabric of which they are made. Over time, cells migrate into the blood or albumin trapped within the Dacron matrix and deposit collagen. As the blood or albumin degrades, it is replaced by the collagen, producing a vessel with some properties similar to those of natural blood vessels. 

Alanine signal generation in bone, 367 heat response, 357 signal production threshold, 367 Zhoukoudian bone, 374 Albumin, trapped, 399 Albumin in body fluids, 15 Albumin in tissue extracts and body fluids, 400 ... 

A major contribution of the free-radical scavenging activity in blood plasma is attributable to the macro-molecular proteins (Wayner et al., 1985) of which albumin is a primary component and trapping agertt (Holt et al., 1984). Serum sulphydryl levels, primarily albumin-related, are decreased in subjects with rheumatoid complicated coalworkers pneumoconiosis, indicative of exacerbated inflammatory R.OM production (Thomas and Evans, 1975). Experimental asbestos inhalation in rats leads to an adaptive but evidendy insufficient response by an increase in endogenous antioxidant enzymes (Janssen etal., 1990). Protection of the vascular endothelium against iron-mediated ROM generation and injury is afforded by the iron sequestiant protein ferritin (Balia et al., 1992). 

Example The ESI mass spectrum and the charge-deconvoluted molecular weights (inset) of bovine serum albumine (BSA) as obtained from a quadrupole ion trap instrument are compared below (Fig. 11.19). Ion series A belongs to the noncovalent BSA dimer, series B results from the monomer. [24]... 

Lung scanning I Trapping of microspheres in Albumin microspheres 643... 

Albumine-Cu2+ complexes are similarly reduced by thiols and then react with H202 (Ozawa et al. 1993). The OH radical thus formed has been detected by spin trapping. 

Figure 15.10 Biocompatible microfabrication allows trapping of a single bacterium. (A, B) SEM images of a bovine serum albumin microcontainer. (C) SEM of a container after the entrance was plugged with a bacterium inside. (D) Sequence showing the container before (1) and immediately after (2) fabrication of a plug to trap the bacterium (arrow scale bar, 10 pirn.). Cell division eventually fills the trap with no loss of bacteria (3-6) (reprinted with permission from [17] 2007 American Chemical Society).

A double-antibody, trapping ELISA was developed that used biotinylated HSA-1 to detect the presence of albumin bound to an unsolubilized second antibody, HSA-2, which was reactive with an epitope common to... 

---