Airway epithelial cell lines

Forbes B (2000) Human airway epithelial cell lines for in vitro drug transport and metabolism studies. Pharm Sci Technol Today 3(1) 18-27. 

Florea BI, Cassara ML, Junginger HE, Borchard G (2003) Drug transport and metabolism characteristics of the human airway epithelial cell line Calu-3. J Control Release 87(1-3) 131-138. 

Shen, B.-Q., W. E. Finkbeiner, J. J. Wine, R. J. Mrsny, and J. H. Widdicombe. 1994. Calu-3 A human airway epithelial cell line which shows cAMP-dependent Cl secretion. Am J Physiol 266 L493-501. 

Andersson C, Servetnyk Z, Roomans GM. 2003. Activation of CFTR by genistein in human airway epithelial cell lines. Biochem Biophys Res Commun 308 518-522. 

Tomee JF, Wierenga AT J, Hiemstra PS, KauSman HE Proteases from A. fumigatus induce release of proinflammatory cytokines and cell detachment in airway epithelial cell lines. J Infect Dis 1997 176 300-303. 

Shan J, Liao J, Huang J et al (2012) Bicarbonate-dependent chloride transport drives fluid secretion by the human airway epithelial cell line Calu-3. J Physiol 590(Pt 21) 5273-5297... 

Ramesh Babu PB, Chidekel A, Utidjian L, Shaffer TH (2004) Regulation of apical surface fluid and protein secretion in human airway epithelial cell line Calu-3. Biochem Biophys Res Commun 319(4) 1132-1137... 

Cowley EA, Linsdell P (2002) Oxidant stress stimulates anion secretion from the human airway epithelial cell line Calu-3 implications for cystic fibrosis lung disease. J Physiol 543(Pt 1) 201-209... 

Borger P, Koeter GH, Timmerman JA, Vellenga E, Tomee IF, Kauffman HE. Proteases from Aspergillus fumigatus induce interleukin (IL)-6 and IL-8 production in airway epithelial cell lines hy transcriptional mechanisms. J Infect Dis 1999 180 1267-1274. 

Cells were grown to confluence on Transwell filters. Calu-3 cells are an airway epithelial cell line rat alveolar cells are a primary culture of alveolar epithelium. Experiments were run in triplicate. 

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