Agents sodium acetylide

Next an alkyl halide (the alkylating agent) is added to the solution of sodium acetylide Acetylide ion acts as a nucleophile displacing halide from carbon and forming a new carbon-carbon bond Substitution occurs by an 8 2 mechanism... 

A group of arylalkylketones containing a basic substituent in the side chain shows CNS activities. Roletamide (190) is a hypnotic agent. It is prepared from 3,4,5-trimethoxybenzaldehyde (187) by addition of sodium acetylide (to give 188), followed by Jones oxidation of ethynylarylketone 189. Michael addition... 

FERROUS CHLORIDE TETRA-HYDRATE (7758-94-3) FeCl Contact with ethylene oxide may initiate polymerization. Reacts violently with reducing agents, including hydrides, nitrides, and sulfides acrolein, alcohols, chlorine trifluoride, ethers, fluorine, hydrazine, hydrazinium perchlorate, hydrogen peroxide, finely divided aluminum or magnesium, peroxyfuroic acid, sodium acetylide. Sensitizes most organic azides which are unstable shock and heat-sensitive explosives. Forms explosive materials with l,3-di(5-tetrazoyl)triazene, potassium,sodium. Incompatible with glycidol, isopropyl chlorocarbonate, nitrosyl perchlorate, sodium borohydride. Aqueous solution attacks metals. 

SULFURIC ACID, BARIUM SALT (7727-43-7) BaS04 Noncombustible solid. An oxidizer. Violent reaction with dimethyl sulfoxide, sodium acetylide, finely divided carbon, aliuninum, magnesium, zirconium, and possibly other active metals, especially in the presence of elevated temperatures. Incompatible with reducing agents aluminmn, potassium, phosphorus. When heated to decomposition, forms toxic sulfur oxides. 

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