Aframomum species

Phenylbutenoid dimers from the rhizomes of Zingiber cassumunar. Phytochemistry 1993 32(2) 357-363. ZO082 Ayafor, J. F., M. H. K. Tchuendem, B. Nyasse, F. Tillequin, and H. Anke. Aframodial and other bioactive diterpenoids from Aframomum species. Pure Appl Chem 1994 66(10/11) 2327-2330. 

B (15), in addition to compound 9 [12]. Compounds 13-15 showed weak anti-microbial and cytotoxic activities. The biological activity of 9 was briefly reviewed and ten other Cameroonian Aframomum species were investigated as potentially better sources for 9 [13]. 

The seeds of Aframomum hanburyi K. Schum. (Zingiberaceae) are used as an antidote and ingredient in certain medicinal preparations in Cameroon [93]. From an acetone extract of the seeds of this plant, two sweet dihydroflavonols, 3-acetoxy-5,7-dihydroxy-4 -methoxyflavanone (68) and 2/ ,3/ -(+)-3-acetoxy-5,7,4 -trihydroxyflavanone (69), were isolated [93]. 3-Acetoxy-5,7-dihydroxy-4 -methoxyflavanone (68) was previously isolated from a different species, Aframomum pruinosum Gagnepain [112]. However, the sweetness intensities of these compounds were not indicated [93,112]. The previously known 2R,2>R)-dihydroquercetin 3-0-acetate (71) which was rated as 80 times sweeter than sucrose, was isolated from Tessaria dodoneifolia (Hook. Am.)... 

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