Aflatoxins genes potentially involved

Table I. Genes Potentially Involved in Aflatoxin Formation Identified...

The phenolic compounds shown to reduce aflatoxin production in response to oxidative stress have potential as tools to investigate functional elucidation of the genes involved but this is limited by the absence of a practical gene transformation system. In the absence of a direct approach with A flavus, use can be made of the yeast Saccharomyces cerevisiae, for which numerous stress response pathways have been characterized [34]. Selected 5. cerevisiae strains, including mutants with single gene deletions, have been used as a model to evaluate phenotypic response to oxidative stress induced by H2O2 [35]. 

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