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Affinity properties, monoclonal antibody tissue

Boron seems to have an affinity for cancerous tumors, and this property has been exploited in radiation therapy (Hamada et al. 1983 Hatanaka 1986). Boron-10 has been used in neutron capture therapy to cure malignant sarcomas implanted in the hind legs of mice, as well as spontaneous malignant melanomas in pigs (Slatkin etal. 1986). The sulfhydral borane monomer (Bi2HnSH) is used as a B-10 carrier in neutron therapy of malignant human brain tumors and seems to be most effective at 30 pg B-lO/kg tissue (Hatanaka 1986). Polyhedral boranes attached to monoclonal antibodies that are tumor specific may become useful in tumor therapy by neutron irradiation (Parry... [Pg.1549]

See other pages where Affinity properties, monoclonal antibody tissue is mentioned: [Pg.317]    [Pg.147]    [Pg.388]    [Pg.144]    [Pg.1712]    [Pg.334]    [Pg.338]    [Pg.100]   


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Antibodies properties

Monoclonal antibodies affinity

Tissue affinity

Tissues properties

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