Adipic acid dichloride

Triodo-3-amino benzoic acid Adipic acid dichloride... 

Adenosine-5 -monophosphoric acid Papaverine monophosadenine Adipic acid dichloride lodipamide Adrenalin... 

The amino-modified support was reacted with adipic acid dichloride and, after hydrolysis, was coupled with 4-iodophenylhydrazine 128 to yield the immobihzed iodobenzene 129. Intermediate 129 was then employed in Pd-mediated C-C couplings (Stille, Heck, Suzuki, Sonogashira) to yield, for example, compounds 130 and 131. The final products 132 and 133 were obtained in good to excellent yields by oxidation of 130 and 131, respectively. 

Diacylation products should be obtained by acylation reactions with dicarboxylic acid dichlorides. We carried out the reaction of methyl 10-undecenoate [2b] with adipic acid dichloride and EtA.lCl2 in a ratio of 2 1 4 (Scheme 3). After a reaction time of 2 h at room temperatoe, the product was crystallized from petroleum ether/ether (9 1) and identified as the methyl diketocarboxylate [9]. The aeylation took place at only one acyl chloride functionality of the dicarboxylic acid. The second acyl chloride functionality reacted with one equivalent of EtAlCl2in a Grignard analogous reaction to give the ethyl ketone. 

SCHEME 3. Ethylaluminum dichloride-induced acylation of methyl 10-undecenoate [2b] with adipic acid dichloride. 

The first industrial success in step polymerisation was the synthesis and development by Carothers and co-workers at DuPont of the famous polyamide Nylon 6-6, starting from hexamethylene diamine and adipic acid dichloride. As shown in Equation 3.1, this reaction is favoured by elimination of hydrochloric acid. 

The main products from the reaction of l-bromo-6 (2-hydroxyethoxy)-cyclohexene (272) and its chloro-analogue with potassium t-butoxide in DMSO at 60—70 °C are the cyclohex-2-enone ethylene ketal (273) and 2,5-dioxabicyclo[4,4,0]deo7-ene (274), and not the 6-ene (275). Dehydrochlorination of adipic acid dichlorides in the presence of aldehydes or ketones yields 4,5,6,7-tetrahydrocyclopenta-l,3-dioxin-4-ones (276). Analogously, the compounds (277) and (278) can be obtained by... 

Process Economics Program Report SRI International. Menlo Park, CA, Isocyanates IE, Propylene Oxide 2E, Vinyl Chloride 5D, Terephthalic Acid and Dimethyl Terephthalate 9E, Phenol 22C, Xylene Separation 25C, BTX, Aromatics 30A, o-Xylene 34 A, m-Xylene 25 A, p-Xylene 93-3-4, Ethylbenzene/Styrene 33C, Phthalic Anhydride 34B, Glycerine and Intermediates 58, Aniline and Derivatives 76C, Bisphenol A and Phosgene 81, C1 Chlorinated Hydrocarbons 126, Chlorinated Solvent 48, Chlorofluorocarbon Alternatives 201, Reforming for BTX 129, Aromatics Processes 182 A, Propylene Oxide Derivatives 198, Acetaldehyde 24 A2, 91-1-3, Acetic Acid 37 B, Acetylene 16A, Adipic Acid 3 B, Ammonia 44 A, Caprolactam 7 C, Carbon Disulfide 171 A, Cumene 92-3-4, 22 B, 219, MDA 1 D, Ethanol 53 A, 85-2-4, Ethylene Dichloride/Vinyl Chloride 5 C, Formaldehyde 23 A, Hexamethylenediamine (HMDA) 31 B, Hydrogen Cyanide 76-3-4, Maleic Anhydride 46 C, Methane (Natural Gas) 191, Synthesis Gas 146, 148, 191 A, Methanol 148, 43 B, 93-2-2, Methyl Methacrylate 11 D, Nylon 6-41 B, Nylon 6,6-54 B, Ethylene/Propylene 29 A, Urea 56 A, Vinyl Acetate 15 A. 

Acetaldehyde Acetophenone Adipic acid Aniline Anthranilic acid Benzoguanamine 3,3, 4,4 -Benzophenone tetracarboxylic dianhydride 1,2,4-Butanetriol n-Butyraldehyde Caprolactam Ceteareth-30 Citric acid Dicyclopentadiene Diethyl aniline Dimer acid N,N-Dimethylaniline Dodecenylsuccinic anhydride Epichlorohydrin Ethylene dichloride Formaldehyde Furfural Hexahydrophthalic anhydride Hexamethylene glycol ... 

When, for example, piperazine, ethylene glycol, phosgene, and adipyl dichloride are simultaneously polycondensed, a copolymer with a more or less random distribution of monomeric units is produced. In this case, however, the sequence of monomeric units is still regulated by the fact that a B monomeric unit (carbonic acid or adipic acid) can only be followed by an A monomeric unit (piperazine or ethylene glycol). 

Draw the product from the reaction of the acid dichloride of adipic acid and an excess of 1-aminopropane. 

One form of nylon is formed by the reaction of the acid dichloride of 1,6-hexanedioic acid (adipic acid) and 1,6-hexanediamine. Draw a reasonable structure for this form of nylon (called Nylon 66). 

For the product from ditriethylammonium adipate and phenylphosphonic dichloride the following pertinent assignments are made (all bands given in cm ) intense band at 1280 in both phenylphosphoric dichloride and product assigned to P = 0 stretching presence of the P-phenyl moiety from the presence of bands at 1420 (1445 in POOCl itself) and 1015 (same for POOCl ) in the product shift or carbonyl from 1680 for terephthalic acid itself, and 1645 for ditriethylammonium terephthalate to 1660 for the product consistent with ester or anhydride formation presence of new peaks at 1065 and 1110 attributed to stretching in the -P-O-C moiety appearance of bands characteristic of the presence of the phenyl and phenylene moieties at 525, 555, 680 (small spike), combined band with spikes at 720 and 725, and 780 (POOCI2 exhibits bands at 790, 720 and 755 ditriethylamine terephthalate exhibits bands at 500, 520, 550, 690, 725, and 770). 

Elemental analysis for tin was conducted as described in reference 12 except that one drop of water and concentrated nitric acid (10 drops) are added subsequent to the sodium fusion and this mixture is heated until brown fumes are evolved. Also, the stannic sulfide is heated in air converting it to stannic oxide which is weighed and this weight utilized in determining the percentage tin. This process is not suitable for extremely volatile organo-stannanes such as dibutyltin dichloride, but is suitable for tin polyesters, polyethers and polyamines. Tin polyesters were utilized as test compounds. Thus, the polyester derived from disodium adipate and dibutyltin dichloride was found to contain 31 percent tin and the calculated value is 31 percent. 

In a very similar way a simple receptor for dicarboxylic acids can be constmcted from the reaction of 2-aminopicoline with terephthaloyl dichloride. Diamide 3 now possesses two bidentate binding regions at a distance apart that coresponds to the spacing of the carboxylic acid groups in adipic or glutaric acid. Thus 3 would be expected to bind to appropriately lengthed dicarboxylic acids via four hydrogen bonds as in 4. 

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