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Adenomatous polyposis coli function

Adenomatous Polyposis Coli Rodent Model Adenomatous polyposis coli (APC) is a dual-function tumor suppressor gene and encodes a protein that has been implicated in a variety of cellular functions including cellular proliferation, differentiation, cytoskeleton regulation, migration, and apoptosis (Neufeld, 2009 Minde et al., 2011 Perez-Sayans et al., 2012). Mechanistically, APC regulates levels of p-catenin, an important mediator of... [Pg.277]

See other pages where Adenomatous polyposis coli function is mentioned: [Pg.309]    [Pg.309]    [Pg.784]    [Pg.2283]    [Pg.2388]    [Pg.507]    [Pg.127]    [Pg.458]    [Pg.328]    [Pg.600]    [Pg.690]   
See also in sourсe #XX -- [ Pg.12 , Pg.14 ]



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