Additives genetic activity

Similarly, the wild type of CCMV could be chemically derivatized using amine-reactive fluorescent anhydrides or via activation of surface-exposed carboxylates and subsequent reaction with fluorophores bearing nucleophilic amine groups. In addition, genetically engineered CCMV with surface-exposed cysteine residues could be used for additional thiol selective attachment of fluorophores and peptides. 

While much of our understanding of TCDD impacts on genetic activity is derived from studies on liver, studies of other tissues (e.g. skin, thymus) are likely to reveal additional TCDD-responsive genes, which exhibit tissue-specific expression [170]. Analyses of the mechanism of dioxin action in such systems appear likely to reveal additional factors that influence the susceptibility of a particular tissue to TCDD. 

Table 7 lists examples of food additives possessing genetic activity. Some of the additives, such as Butter Yellow, have been banned, whereas others, such as nitrite or sulphite, are still being used. The table is presented for illustrative purposes only and is not intended to be complete. 

EXAMPLES OF CURRENT AND FORMER FOOD ADDITIVES HAVING GENETIC ACTIVITY... 

---