Acylpalladation reactions

Although the Pd-catalyzed alkene-CO copolymerization reaction must involve a series of acylpalladation reactions, it is outside the scope of this chapter. And, the readers are referred to recent reviews and pertinent references cited therein [27-29]. As such, the cyclic carbonylation reactions of dienes were of limited synthetic utility because of difficulties in controlling regiochemistry and other aspects of importance in fine chemicals synthesis. Whatever the reasons might have been, little had been reported further until the 1980s. 

Coperet C, Negishi E (2002) Intramolecular Acylpalladation Intramolecular Acylpalladation Reactions with Alkenes, Alkynes, and Related Unsaturated Compounds. In Negishi E, de Meijere A (eds) Handbook of Organopalladium Chemistry for Organic Synthesis. Wiley, New York, p 2519... 

VI.4.1.1 Intramolecular Acylpalladation Reactions with Alkenes, Alkynes, and Related Unsaturated Compounds... 

In all of the three cyclic acylpalladation reactions, that is. Types I-III Ac-Pd processes, polymeric acylpalladation discussed in Sect. VI.4.2 and direct noncarbonylative carbopal-ladation discussed in Sect. IV.3.3 can be not only serious side reactions but even dominant processes depending on the reaction conditions. The polymeric acylpalladation process... 

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