Activity, glycosyl group

Thioglycosides containing free OH groups readily tolerate silver triflate-pro-moted glycosylations with glycosyl bromides and chlorides, and also tin(II) chloride-silver perchlorate-activated glycosylation, and several examples have... 

In all of the foregoing examples, an activated derivative of the nucleotide has been employed for generating the pyrophosphate link. An attempt to use an activated glycosyl phosphate failed 311 the only product identified from the reaction between /3-D-glucopyranosyl phosphoramidate (68) and uridine 5 -phosphate was the cyclic phosphate 69. The ease of participation of the sterically accessible, C-2 hydroxyl group probably accounts for this result. The usual procedure... 

Further studies will be needed in order to resolve the intriguing question as to how the glycosyl groups of the activated sugars that are usually found in the cytoplasm are transferred to the growing chain of the lipid-bound oligosaccharide inside the lumen of the endoplasmic reticulum. 

Glycosyl group Activated form With a-linked sugar With linked sugar Total number... 

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