Active targeting controlled drug delivery

One characteristic quality change in this field is that the sharp distinction between active substances and additives has disappeared. The reason for this is that in controlled drug delivery systems the sustained, pulsatile, targeted drug release can almost be regarded as an independent therapeutic effect. 

Ultimately, for Pt(IV) anticancer drugs, a combination of incorporation of bioactive ligands that specifically target cancer cells, control over ligand-exchange kinetics, and selective activation by light would allow for temporal and spatial control of drug delivery and activation. 

Note A polymer drug is usually used to provide drug delivery targeted to an organ and controlled release of an active drug at the target organ. 

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