Activation of Matrix Metalloproteinases in Spinal Cord Injury

5 Activation of Matrix Metalloproteinases in Spinal Cord Injury 

Matrix metalloproteinases (MMPs) are a family of extracellular zinc-dependent endopeptidases that hydrolyze the extracellular matrix and other extracellular proteins (Malemud, 2006). These enzymes are involved in both injury and repair mechanisms in brain and spinal cord. Three members of the MMP family, MMP-2, 

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