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Activation and condensation of protected peptide fragments

DMSO is the best solvent in terms of solvating properties, purity of products, and suppression of racemization. [Pg.222]

The C-component must be applied in the highest possible concentration. [Pg.222]

Dissolve the protected fragment (3-5-fold excess over the resin bound N-component) and 2.0 eq HOBt in the highest possible concentration in DMSO. [Pg.222]

Add to this solution the dry resin without pre-swelling and shake for 6h. [Pg.222]

Check the condensation reaction by using the Kaiser test, TLC, and [Pg.222]

See other pages where Activation and condensation of protected peptide fragments is mentioned: [Pg.221]   


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Activating fragments

Active condensations

Fragment condensation

Fragment protected

Fragmentation activity

Fragmentation of Peptides

Fragmentation peptides

Peptide active

Peptide activity

Peptide fragments, activity

Peptide protection

Peptides activation

Peptides condensation

Peptides fragment condensation

Protected peptides

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