Action for the Anticonvulsants

These three mechanisms of action for the anticonvulsants shall now be discussed briefly in the sections that follows  

It has been observed that both the Na and CL ions are invariably present at much higher concentration outside the cell , whereas K, charged proteins, and organic cations are more abundantly available very much inside the cell . It is an universal fact that only the smaller ions can permeate through the membrane, whereas the larger ions or proteins fail to do so therefore, the neuronal membranes 

The actual requirement for a neuron, whether or not an action potential is accomplished exclusively governed by the achievable equilibrium (or balance) between the prevailing excitatory and inhibitory stimulation. It has been established beyond any reasonable doubt that GABA is solely responsible as the predominant inhibitory transmitter in the brain. The modus operandi are as stated below  

9 GABA binds to two receptor types viz., GABA and GABAg 

9 neuronal hyperpolarization is caused when GABA receptors takes place on Cl ion channels, and subsequently the binding of GABA results into chloride influx. 

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