Actigall - Ursodiol

Galls tone-solubilizing (gallstone-dissolving) drugs, such as ursodiol (Actigall), suppress die manufacture of cholesterol and cholic acid by die liver. The suppression of die manufacture of cholesterol and cholic add may ultimately result in a decrease in die size of radiolucent gallstones. 

Ursodeoxycholic acid = ursodiol Actigall, Destolit, Ursofalk... 

Parenteral 120 mL bottle for bile duct perfusion Ursodiol (Actigall)... 

Ultravist iopromide ursodiol Actigall, Adursall, Arsacol, Biliepar, Cholacid, Cholit-... 

Dried bile from the Himalayan bear (Yutan) has been used for centuries in China to treat liver disease. UDCA (ursodiol, Actigall) is a hydrophilic, dehydroxylated bile acid that is formed by epimerization of the bile acid, chenodeoxycholic acid (CDCA Chenodiol), in the gut by intestinal bacteria. It comprises approximately 1 to 3% of the total bile acid pool in human beings but is present at much higher concentrations in bears. When administered orally, litholytic bile acids, such as chenodiol and ursodiol, can alter relative concentrations of bile acids, decrease biliary lipid secretion, and reduce the cholesterol content of the bile so that it is less lithogenic. Ursodiol also may have cytoprotective effects on hepatocytes and effects on the immune system that account for some of its beneficial effects in cholestatic liver diseases. 

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