Acoustic chemometrics as a PAT tool

In this chapter we illustrate development of acoustic chemometrics for process monitoring in the chemical engineering realm with a feasibility survey of the application potential for industrial applications. Earlier studies [3-7] describe the initial small- to medium-scale pilot experiments behind this approach, collectively giving a broad introduction to the application of acoustic chemometric for liquid flow in pipelines [3,7], industrial granulation processes [7-9,11] and similar process technological regimens. Since a full introduction to acoustic chemometrics has been published elsewhere [3-7], only an operational summary is provided in this chapter. 

Many earlier successful PLS prediction models (which in this chapter are presented as examples from industrial production processes) signify that acoustic chemometrics has matured into a proven on-line technology in the PAT domain. It is a salient point here that all were evaluated using test set validation [2]. 

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