Aconitum chasmanthum

A. volubile Pall, ex Koelle var. oligotrichum Kitag., A. napellus L., A. koreanum R. Raymund, A. deinorrhizum Stapf., Aconitum chasmanthum Stapf., A. fischeri Reichb. [Pg.347]

Structure and Absolute Configuration of Chasmanine 14 -Benzoate Hydrochloride.—The full report on the X-ray crystallographic structure determination of this derivative of chasmanine, isolated from the roots of Aconitum chasmanthum Stapf, has appeared9 (cf. Vol. 7, p. 253). The structure was computed to be (1) by direct methods. The absolute configuration as determined by the R-ratio test is IS, 4S, 5R, 6R, 1R, 8S, 9R, 1 OR, 11S, 13R, 14S, 16S, 17R.10 This structure determination confirmed the structures of chasmanine (2) and homochasmanine (3) that had previously been proposed on the basis of chemical and spectral data.11... [Pg.220]

A reexamination of the roots of Aconitum chasmanthum revealed the presence of four new alkaloids—chasmaconitine, chasmanthinine, chasmanine, and homochasmanine—in addition to indaconitine which was originally described in 1905 (124). Chasmanine and homochasmanine will be discussed in the following section. [Pg.83]

Homochasmanine (CCCXXXII) is the fifth alkaloid characterized from Aconitum chasmanthum and has the empirical formula C26H43NO6, which contains one CH2 more than chasmanine (137). The alkaloid is unstable and decomposes slowly on standing. The NMR spectrum shows the triplet characteristics of an A-ethyl group and also five methoxyl... [Pg.93]

Aconitum chasmanthum Chemical and spectral analysis Refs. 20, 68... [Pg.84]

A. carmichaelii, A. chasmanthum, A. deinorrhizum, A. Jischeri, Aconitum jaluense, A. koreanum,... [Pg.436]

Aconitum balfouri, A. carmichaelii, A. chasmanthum, A. chinense, A. deinorrhizum, A. fischeri, A. jaluense, A. koreanum, A. kusnezoffii, A. laciniatum, A. napellus, A. pariculigerum, A. praeparata,... [Pg.453]

Acnisal salicylic acid, aconiazide [inn] is an isoniazid analogue and an ANTITUBERCULAR and ANTIBACTERIAL AGENT, aconitine is an alkaloid from monk s hood or wolfsbane (Aconitum napellus) and other Aconltum spp. (Ranunculaceae). It is a NEUROTOXiN implicated in poisoning by A. spp., especially, 4. chasmanthum in India. Experimentally, it is a SODIUM-CHANNEL ACTIVATOR that binds to Na -channels, slows inactivation, shifts inactivation to a more negative value, and alters ion specificity. This results in repetitive firing of neurons, with marked effects on the heart including positive inotropism and arrhythmias. Aconitine (and the related alkaloid delphinine) were formerly used in... [Pg.4]

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See also in sourсe #XX -- [ Pg.295 , Pg.309 ]

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