Acetylcholinesterase inhibitors pharmacology

Colovic, M.B., Krstic, D.Z., Lazarevic-Pasti, T.D., et al., 2013. Acetylcholinesterase inhibitors pharmacology and toxicology. Curr. Neuropharmacol. 11,315-335. 

People with dementia and their carers require access to a variety of health and social care services for treatment, information and counselling, community-based support, respite care and long-term residential care. Treatment may include behavioural therapies (e.g. reality orientation, cognitive stimulation and validation therapy) or pharmacological treatment with acetylcholinesterase inhibitors. 

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Chaudhaery SS, Roy KK, Shakya N, Saxena G, Sammi SR, Nazir A, Nath C, Saxena AK (2010) Novel carbamates as orally active acetylcholinesterase inhibitors found to improve scopolamine-induced cognition impairment pharmacophore-based virtual screening, synthesis, and pharmacology. J Med Chem 53 6490-6505... 

Pharmacology Galantamine is a competitive and reversible inhibitor of acetylcholinesterase. While the precise mechanism of galantamine s action is unknown, it may exert its therapeutic effect by enhancing cholinergic function. Pharmacokinetics ... 

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