Acetyl-D-glucosamine

Another structural variation is the replacement of a hydroxyl group m a carbohydrate by an ammo group to give an ammo sugar The most abundant ammo sugar is one of the oldest and most abundant organic compounds on earth N Acetyl d glucosamine is the... 

Henry reaction of the (V-acetyl-D-glucosamine derived nitrosugar 1 with 2,3-O-cyclohexylidene-D-glyceraldehyde (2) furnishes a single product 3 in 85-90% yield7. 

Partially deacetylated chitin, a cellulose-like biopolymer consisting predominantly of N-acetyl-D-glucosamine chains, in the form of films or crosslinked hydrogels has been used for the delivery of drugs (28,29). The suitability of chitin as a vehicle for the sustained release of drugs was examined using indomethacin and papaverine hydrochloride as model drugs (30). In vitro studies showed that over 80% of the indomethacin was released within 7 hr, whereas papaverine hydrochloride dissolved almost immediately. 

Lysozyme j Hydrolyzes link between N-acetylmura-j mic acid and N-acetyl-D-glucosamine j found in certain bacterial cell walls Abundant in macrophages... 

Aufier dem Aminonucleosid II wurden Verbindungen mit analoger Struktur synthetisiert, die an Stelle der 3-Amino-D-ribose 3-Amino-D-arabinose (12) oder N-Acetyl-D-glucosamin (9) enthalten. 

Die drei isomeren /J-D-Galaktopyranosyl-lV-acetyl-D-glucosamine, namlich die Lacto-iV-biose I (y -l,3), das iV-Acetyl-lactosamin (j8-1,4) und das iV-Acetyl-allolactosamin (fi-, 6) sind auf dem Wege der enzy-matischen Transgalaktosidierung synthetisiert worden. 

Synthesis of /J-u-Galactosides of Y-Acetyl-D-Glucosamine by Various Mammalian Tissues. J. biol. Chemistry 220, 71 (1956). 

Acetamino-furan aus V-Acetyl-D-glucosamin ein Beitrag zur Theorie... 

Stanley, P. G. Liberation of N-Acetyl-D-glucosamine from Ovomucin by... 

The anion of nitromethane adds easily to the carbonyl functions of sugars. This is a useful strategy for extension of the carbon chain.100 2-Acetamido-2-deoxy-P-D-glucose (A-acetyl-D-glucosamine) is the carbohydrate unit of glycoproteins that occurs most often. The nitromethy-lation method provides a straightforward route to a series of C-glycosyl compounds with the acetamido functionality (Eq. 3.62).101... 

N-acetyl-D-glucosamine hexuronie acid (probably D-gluc-uronic acid)... 

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