Acetophenone, 2-hydroxy-5-methOXY 0-NITRO

Cassimjee et al. reported [22] that a variant engineered aminotransferase at TrpOOCys from Chromohacterium violaceum showed a 29-fold increase on spedfidty for synthesis of (S)-phenylethylamine and about fivefold on spedfidty for 4 -substituted acetophenones, where the groups at 4 position were bromo, chloro, hydroxy, methoxy, nitro, methyl, and cyano. The amine donor was isopropylamine. The reaction schemes are shown in Figure 7.5. 

Preparation by reduction of 2-hydroxy-5-methoxy-3-nitro-acetophenone with stannous chloride dihydrate in hydrochloric acid (47%) [2586],... 

Preparation by reduction of 2-hydroxy-4-methoxy-5-nitro-acetophenone [2530] with tin in concentrated hydrochloric acid heated in a water bath... 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

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