Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Acetophenazine Dimaleate

Chemical Name 10-(3-(4-(2-hydroxyethyl)-1-piperazinyl] propyl]phenothiazin-2-yl methyl ketone maleate [Pg.18]

The requisite intermediate. 10-(3-chloropropyl)-2-acety(phenothiazine is prepared as follows To a suspension of sodamide (from 3 grams of sodium) in 300 ml of liquid ammonia is added 30 grams of 2-acetylphenothiazine. After stirring for one hour, there is added 19 grams of 1-bromo-3-chloropropane. The ammonia is allowed to evaporate and the residue is diluted with 200 ml of water. The mixture is extracted with ether and the ether solution is dried over anhydrous sodium sulfate, filtered and concentrated. [Pg.18]

The residue consists of crude 10-(3-chloropropyl)-2-acetylphenothiazine as a viscous oil and is used in the next step without further purification. The crude base obtained from the reaction of 10-(3-chloropropyl)-2-acetylphenothiazine with 1-(2-hydroxyethyl)piperazine is purified by conversion to its dimaleate salt, MP 167°-168.5° from ethanol. [Pg.18]

Bromo-3-chloropropane Acetophenazine dimaleate Oxaflumazine disuccinate Perphenazine Reproterol... [Pg.1618]

Synonym. Acetophenazine Dimaleate Proprietary Name. Tindal C23H29N302S,2C4H404 = 643.7 CAS—5714-00-1... [Pg.315]

Acetone, 315 (metabolite), 691 Acetone-Chloroforme, 444 Acetonylallylbarbituric acid, 398 Acetonylbromoallylbarbituric acid, 398 Acetonylisopropylbarbituric acid, 677 Acetophenazine, 315 Acetophenazine dimaleate, 315 Acetophenazine maleate, 315 Acetophenetidide, 870 Acetophenetidin, 870 Acetopt, 981 Acetorphine, 316 Acetorphine hydrochloride, 316 Acetosulfaminum, 981... [Pg.1176]

Acetophenazine dimaleate Benzyl alcohol, redistilled Diacetylchondocurarine iodide... [Pg.394]

See other pages where Acetophenazine Dimaleate is mentioned: [Pg.18]    [Pg.1611]    [Pg.1748]    [Pg.56]    [Pg.56]    [Pg.394]    [Pg.266]    [Pg.18]    [Pg.1611]    [Pg.1748]    [Pg.18]    [Pg.1611]    [Pg.1748]   


SEARCH



Acetophenazine

© 2024 chempedia.info