Acetic acid organometallic ligands

Detailed mechanistic and theoretical analysis of the key mechanistic steps of the Cativa process, for the Cativa process See Ref 257,257a that is, the iridium-based catalytic carbonylation of methanol to acetic acid, have allowed several groups, " particularly Haynes and co-workers, to unravel the mechanism of the catalytic process. Ir(l) complexes [Ir(CO)(L-L)I] (LL = dppms, dppe, dppmo) provided important mechanistic information about the influence of stereoelectronic ligand effects on the organometallic reactivity of modified metal centers with Mel. The carbonylation of methanol promoted by iridium and rhodium complexes which is at the basis of both Cativa and Monsanto processes for the synthesis of acetic acid will be described in detail in a different chapter of this volume. 

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