Acetic acid, butyryl-, ethyl ester

Acetic acid, butyryl-, ethyl ester [Hexanoic acid, 3-oxo-, ethyl ester] 55, 73, 75 Acetic acid, chloro-, tert-butyl ester [Acetic acid, chloro- 1,1-dimethylethyl ester], 55,94... 

Acenaphthylene, 58, 73 Acetaldehyde, 58, 157 Acetamides, arylalkyl-, 56, 7 Acetanilide, 2,2,2-tnfluoro-, 56, 122 Acetic acid, butyryl-, ethyl ester, 55,73,... 

Synthesis (Kleemann et al. 1999, Janssen (Janssen), 1973 Janssen et al. (Janssen), 1973, Stokbroekx et al., 1973, Niemegeers et al., 1974) ) Treatment of 2-oxo-3,3-diphenyl-tetrahydrofuran, synthesized by treatment of diphenyl-acetic acid ethyl ester with ethylene oxide, with HBr(gas) yields bromo derivative i, which is then converted into butyryl chloride derivative ii by means of thionyl chloride in refluxing chloroform. Reaction of derivative ii with dimethylamine in toluene affords dimethyl (tetrahydro-3,3-diphenyl-2-furylidene)ammonium bromide, which is then condensed with 4-(4-chlorophenyl)-4-piperidinol by means of Na2C03 and Kl in refluxing 4-methyl-2-pentanone to provide loperamide. 

Acetaldehyde ethyl phenethyl acetal Acetaldehyde phenethyl propyl acetal Acetanisole Acetic acid, (cyclohexyloxy)-, 2-propenyl ester Acetisoeugenol 2 -Acetonaphthone Acetophenone Acetyl butyryl Acetylcyclopentanone Acetyl ethyl octanoate... 

Bomyl butyrate Bornyl formate Bomyl isovalerate Bornyl valerate p-Bourbonene 2-Butanol Butan-3-one-2-yl butyrate Butter acids Butter esters n-Butyl acetate Butyl acetoacetate Butyl alcohol n-Butylamine Butyl anthranilate Butyl butyrate Butyl butyryl lactate a-Butylcinnamaldehyde Butyl cinnamate Butyl 2-decenoate Butyl ethyl malonate... 

We have made acyl, benzoyl and butyryl esters/amides of zein. These products were washed with ethyl acetate to remove unreacted acid chlorides or anhydrides. The NMR of these confirmed the acylation. When dianhydride, 1,2,4,5-benzenetetracarboxylic dianhydride (BTCD), was reacted in various levels, slightly crosslinked to highly crosslinked products were obtained. The highly crosslinked product gelled out of the DMF solution. However, the slightly crosslinked (10Jl) zein was still soluble in DMF and we could make bars out of them by compression molding. 

The enzyme is specific for thiol esters of the type of S-acetyl and S-butyryl glutathione. Besides the three thiol esters already discussed, ethyl thiol-acetate, butyl thiolacetate, acetyl thioglycolic acid, acetyl mercapto propionic acid, S-acetyl-2 mercaptoethanol, acetyl thiomalic, acetyl coenzyme A, and butjryl coenzyme A were inactive with the purified enzyme. Crude extracts of liver attacked butyl thiolacetate and acetyl coenzyme A slowly. 

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