Accuracy error grid analysis

Clarke WL, Anderson A, Farhy L, Breton M, Gonder-Frederick L, Cox D, Kovatchev B. Evaluating the clinical accuracy of two continuous glucose sensors using continuous glucose-error grid analysis. Diabetes Care 2005, 28, 2412-2417. 

Figure 3.2 The effect of prolonged subcutaneous implantation on biosensor function. Blood glucose values shown in solid circles and glucose sensor values in the continuous lines. The early study (top panel), but not the late study (bottom), shows excellent sensor accuracy and minimal lag between blood glucose and sensed glucose values. MARD (mean absolute relative difference) refers to a sensor accuracy metric. EGA refers to the Clarke error grid analysis accuracy metric.

Error grid analysis has recently been extended for the evaluation of continuous glucose monitoring sensors. Kovatchev BP, Gonder-Frederick LA, Cox DJ, and Clarke WL. 2004. Evaluating the accuracy of continuous glucose-monitoring sensors. Diabetes Care 27 1922-1928. 

When Qp u(, . = 0(1) is accepted in some suitable grid norm (2 ) built into stability theorems, we might achieve economical factorized scheme (38) the error of approximation changes within a quantity of 0(r2). Following these procedures, we obtain economical factorized schemes of second-order accuracy in r as stated before due to the extra smoothness of the solution u. Such a stability analysis of schemes (36) and (39) is mostly based on the further treatment of the operators R and A as linear operators acting from... 

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