Accelerator mass spectrometry liquid scintillation counting

R. C. Garner, J. V. Garner, S. Gregory, M. Whattam, A. Calam, D. Leong. Comparison of the absorption of micronized (daflon 500 mg) and nonmicronized 14C-diosmin tablets after oral administration to healthy volunteers by accelerator mass spectrometry and liquid scintillation counting. J. Pharm. Sci. 2002, 91, 32— 40. 

Principal characteristics of small sample liquid scintillation counting (lsc), gas proportional low-level counting (11c) and atom counting by accelerator mass spectrometry (AMS) are summarized in Table 1, and systems we have used are shown in figure 1. The most important differences (apart from cost and availability)... 

Measurement Techniques. Light isotopes Concentrations of were determined radiometrically after synthesis of propane (13) in a proportional counter after about twenty-fold electrolytical enrichment of (14), The C content of large samples (. 5 g C) were determined by liquid scintillation counting after synthesis of benzene (15) fi-om CO2 which was extracted fi-om the water sample after acidification. The C content of small samples (<0.5 g C) were measured by accelerator mass spectrometry (AMS) W the Isotrace Laboratory of the University of Toronto. The C, and isotopic... 

Gilman, S.D. et al., Analytical performance of accelerator mass spectrometry and liquid scintillation counting for detection of 14C-labeled atrazine metabolites in human urine,... 

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