Accelerated Chemistry Microwave, Sonochemical, and Fluorous Phase Techniques

Accelerated Chemistry Microwave, Sonochemical, and Fluorous Phase Techniques 

KRISTOFER OLOFSSON PETER NILSSON AND MATS LARKED  

Even though many of these techniques in themselves are modem, there has been an interest to develop these methods, and invent new techniques, to further increase the speed of hit identification and lead optimization. In large, and in direct application to this chapter, these efforts can be divided into techniques that increase either the speed of synthesis, such as microwave and sonochemical approaches, or the speed of separation, such as fluorous techniques. 

Microwave heating is today an important and accepted method of heating in preparative chemistry.The attractions of microwave-heated technologies are 

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