Acanthopanax gracilistylus

Fujikawa et al. made the interesting observation that an extract from the stem bark given orally at a dose of 250 mg/kg once a day for 2 weeks protects rats against MPTP-induced Parkinsonian bradykinesia and catalepsy and inhibited neuronal loss of dopamine (70). The active constituents involved here are unknown. Note that the plant abounds with pentacyclic oleanene saponins (71-73). Note that Acanthopanax species are known to elaborate a series of diterpenes, a group that has the potency to bind to dopamine receptors, as reported in Vitex agnus-castus. Are diterpenes involved in the dopaminergic properties of Acanthopanax gracilistylus W. W. Sm. ... 

Shan, . E., Z. Kazuya, S. Tsutomu, Y. Yasuhiro, and U. Yamashita. 2000. Chinese medicinal herb, Acanthopanax gracilistylus, extract induces cell cycle arrest of human tumor cells in vitro. Jpn. J. Cancer Res. 91 383-389. 

Tang, X., Y. Ma, and P. Li. 1995. Separation and identification of the anti-inflammatory diterpene from the root cortices of Acanthopanax gracilistylus W. W. Smith. Zhongguo Zhongyao Zazhi 20 231. 

Sapindus mukorossi Gaertner Acanthopanax gracilistylus, A. spinosum Miq. 

Acanthopanax gracilistylus, A. spinosum Jatropha gospiifolia, J. curcas Sinapis alba Arachis hypogaea... 

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