Absence of Calponin Phosphorylation during Smooth Muscle Contraction

ABSENCE OF CALPONIN PHOSPHORYLATION DURING SMOOTH MUSCLE CONTRACTION 

On the other hand. Winder et al. (1993) described CP phosphorylation in carbachol-contracted 

The finding that CP is phosphorylated in vitro but not in the intact muscle is reminiscent of that of the inhibitory component of skeletal muscle troponin, which can be phosphorylated (Stull et al., 1972) and dephosphorylated (England et al., 1972) in vitro but is not phosphorylated during contraction of intact skeletal muscle (Barany et al., 1974). Apparently, protein residues that are free for phosphorylation in vitro may participate in bond formation or are buried in situ and. 

Since LC20 phosphorylation-dephosphorylation goes parallel with the mechanical cycle of the muscle, it has the potential for regulating smooth muscle contraction. The phosphorylation of DS may be involved in force maintenance during sustained contraction. 

XL PROTEIN PHOSPHORYLATION IN PHORBOL ESTER-TREATED SMOOTH MUSCLE 

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IX. ABSENCE OF CALPONIN PHOSPHORYLATION DURING SMOOTH MUSCLE CONTRACTION... 

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