Abscisic acid analogs

Abscisic acid analogs for probing the mechanism of abscisic acid reception and inactivation... 

ABSCISIC ACID ANALOGS FOR PROBING THE MECHANISM OF ABSCISIC ACID RECEPTION AND... 

Chen, S.C., and MacTaggart, J.M., Abscisic acid analogs with a geometrically rigid conjugated acid side-chain, Agric. Biol. Chem., 50, 1097, 1986. 

Y. Todoroki N. Hirai, Abscisic Analogs for Probing the Mechanism of Abscisic Acid Reception and Inactivation. In Studies in Natural Product Chemistry Ed. Atta-ur-Rahman, Ed. Elsevier Amsterdam, 2002 Vol. 27, pp 321-360. 

Of the analogous compounds related to a particular hormone, attention must be drawn to the large group of synthetic auxins, to the synthetic cytokinins (- recently not only adenine, but also urea derivatives -) and to the ethylene generators ( 1, 2). An extension of the range of analogous compounds is indicated in the case of abscisic acid, as well (3j. 

The analogous or, ) - /,5-unsaturated ester on the other hand, did not undergo cyclization under these conditions [159], whereas the methyl ester of abscisic acid [Eq. (18)], which also contains an a,) -, 5-unsaturated ester function, undergoes cyclization upon reduction in MeCN (containing AcOH) [160]. 

ABSTRACT More than 100 abscisic acid (ABA) analogs have been reported so far. Some were synthesized to clarify structure-activity relationships, and others were developed as tools for investigating the molecular mechanism of ABA action. These analogs, especially those that can be useful tools for studying ABA reception and catabolic inactivation, are summarized together with their design concepts, structural properties and bioactivities. 

In structural terms these fungal metabolites are analogous to the iridoid monoterpenoids cf. Chapter 1). Recent studies on the biosynthesis of cyclonerodiol,cyclonerotriol, and abscisic acid (25) are described in Chapter 6. 

A. S. Dimoglo, 1. B. Bersuker, D. P. Popa, and K. 1. Kuchkova, Theor. Eksp. Khim., 5, 590 (1989). Electron-Topological Study of Plant Growth-Regulator Activity in Series of Analogs of the Abscisic Acid. 

It should be mentioned - according to a recent publication (Eef. 25) - that, in analogy to the gibberellins, abscisic acid is biosynthesized, too, in much larger amounts by the fungus Cercospora rosicola (typical secondary metabolite) in comparison to tlie higher plants (acting as hormone). 

Synthesis and Biological Evaluation of Abscisic Acid, Jasmonic Acid, and Its Analogs... 

Plant hormones play inq)ortant roles in controlling many aspects of plant growth and development. Among several conqiounds recognized as plant hormones, only abscisic acid (ABA, 1) and jasmonic acid (JA, 2) are not used practically because of their instability and cost. To overcome diese points, we have made efforts to develop new synthetic routes and new analogs of these hormones. Here we describe our recent advances of these studies. 

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