A Simple Flow Calorimetric Experiment

It has been noted throughout this chapter that flow microcalorimetry can be used for a wide variety of reaction systems. This section will attempt to describe a simple. 

In general, the object of most calorimetric experiments is the quantification of thermodynamic and kinetic parameters. Several recent developments now permit the recovery of such parameters through calculational methods. These are not discussed in detail here for a more detailed discussion, see refs. 8-11. 

A good example of the range of parameters available from flow calorimetric data can be found from the study of enzyme/substrate systems. The kinetic nature of enzyme systems has been previously described by Michaelis and Menten. In the treatment discussed here, the parameters sought are the enthalpy, rate constant, Michaelis constant and the enzyme activity. The following example describes a study on the well-known enzyme substrate system, urea/urease. 

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