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A Kinase Anchoring Proteins

Langeberg LK, Scott JD (2005) A-kinase-anchoring proteins. J Cell Sci 118 3217-3220... [Pg.4]

Beene DL, Scott JD (2007) A-kinase anchoring proteins take shape. Curr Opin Cell Biol 19 192-198... [Pg.19]

The A kinase anchor proteins (AKAP), which are tightly associated with the cytoskeleton, serve as anchors for protein kinase A. In addition to the RII subimit of protein kinase A, the AKAP proteins also bring protein phosphatases and other protein kinases to the cytoskeleton in a targeted fashion. The AKAP79 protein binds protein kinase C and protein phosphatase 2B (calcineurin) as well as the RII subunit. The possibility to bring both a protein kinase and a protein phosphatase to the same place in the cell opens up the prospect of a coordinated and layered regulation of both enzyme activities. [Pg.281]

Now covers the roles of membrane rafts and caveolae in signaling pathways, including the activities of AKAPs (A Kinase Anchoring Proteins) and other scaffold proteins... [Pg.1127]

A-Kinase Anchor Protein 6 Q13023 (h) 1) Protein kinase A-anchoring protein 6 (AKAP6) 2) Muscle A-kinase anchor protein (mAKAP) 3) A-Kinase anchor protein 100 kDa (AKAP100) AKAP6 (h) 14q13.1 (h) 2319 (h)... [Pg.131]

A-Kinase Anchor Protein (AKAP6 or mAKAP) Human 847-874 l-L-l-L LELIASHKAGLKDMLRMIASQWKELQRQ... [Pg.133]

Carr DW, Stofko-Hahn RE, Fraser ID, Cone RD, Scott JD (1992) Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79. J Biol Chem 267 16816-16823. [Pg.139]

Proteinkinase A, cyclic AMP-dependent serine/threonine proteinkinase. Activation by cAMP produces two active catalytic monomers and a regulatory dimer, binding four molecules of cAMP. Type I and type II kinases are distinguished. In the case of the type II kinase, the regulatory chains mediate membrane association and interaction with MAP kinase and AKAP, the A kinase anchoring protein. [Pg.318]

Steen, R.L., Martins, S.B., Tasken, K. and Collas, R. (2000) Recruitment of protein phosphatase 1 to the nuclear envelope by A-kinase anchoring protein AKAP149 is a prerequisite for nuclear lamina assembly. J. Cell Biol. 150, 1251-1262. [Pg.75]

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See also in sourсe #XX -- [ Pg.92 ]



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A-kinase

Anchor protein

Kinases anchoring

Protein kinase A

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