110mIn

Bromofuran [22037-28-1 ] M 147.0, b 38.5 /40min, 50 /110min, 102.5-103 /atm, d 1.661, n 1.4970. Purified by two steam distillations and dried over fresh CaO. It can be dried over Na metal (no obvious reaction) and fractionated. It is not very soluble in H2O but soluble in organic solvents. Freshly distilled, it is a clear oil, but darkens on standing and eventually resinifies. It can be stored for long periods by covering the oil with an alkaline soln of hydroquinone and redistilled when required. It forms a characteristic... 

Calculate the activity of 18F produced when 1 g of 70% enriched H2lsO is irradiated for 1 h with a proton beam of 30 pA/cm2 in a cyclotron. The half-life of18F is 110min and the cross section for the lsO (p, n) 18F reaction is 300 millibam (1 barn = 10 24 cm2). 

Owing to the short half-lives of the radioactive isotopes involved (e.g., t n of carbon-ll=20min, ty-i of fluorine-18 = 110min), radiopharmaceuticals for PET (and related SPECT) imaging are typically produced on-site daily or at facilities in close proximity to the PET imaging center. Radiopharmaceutical production typically requires trained radiochemists, with specific and expensive facilities. Moreover, the short-lived radionuclides involved means that radiochemical reactions must be fast, efficient, and amenable to automation, and new techniques that facilitate radiopharmaceutical production and the ability to meet clinical demand for PET tracers are in demand. Solid-phase synthesis is an attractive synthetic technique to the radiochemist as it bears many of these desirable characteristics. Despite this, solid-phase organic radiosynthesis (SPOR) is a relatively new... 

---