SEARCH Articles Figures Tables A Hit Generation by Virtual Screening Accidents near hits/misses Affinity-Based Screening Methodologies and Their Application in the Hit-to-Lead Phase Application strategies hit optimization Approaches to Searching for Hits Bullet hit squib Chemoinformatic Tools for Library Design and the Hit-to-Lead Process A Users Perspective Computational hit identification Database hits, statistically significant Defining Inhibition, Signal Robustness, and Hit Criteria Direct hit Drug-like hits Early Optimization or Hit-to-Lead Libraries Epigenetic Targets in Drug Discovery Cell-Based Assays for HDAC Inhibitor Hit Validation Experimental Filtering the ADMET Characterization of a Hit Collection Filtering hits to leads Genetic Toxicity In Vitro Approaches for Hit and Lead Profiling Goodness of hit list HIT Matrix High hit rate Hit Generation by Rational Library Design Hit Identification Strategies Hit Quality Hit Rate Parameter and Chemical Profiling Hit Search Through Database Mining Hit Units for Nonlinear Cases Hit Validation and Progression Hit and Lead Discovery Hit and lead Hit and lead profiling Hit compounds Hit confirmation Hit evaluation phase Hit finding Hit follow Hit identification Hit kinetics Hit list Hit molecules Hit optimization Hit optimization strategies Hit probabilities Hit quality index Hit rate Hit threshold Hit to Lead also Known as Closed Loop Hit to lead Hit to lead program Hit triage Hit validation Hit-to-lead optimization Hit-to-lead phase Hit-to-lead process Hit-to-lead stage Hit-to-lead strategies Hit/lead generation Hitachi high throughput purification hit rate Hitness models, risk calculation Hits against Receptors Hitting the right spot Latent hit Lead-like hits Lipophilic hits Maximum number of hits Melting and boiling points, HIT Methods for Fragment Hit Follow-Up Minimum hit quality Multi-hit models Near hits Near hits reporting One-hit models Postprocessing of Pharmacophore-Based Screening Hits Prioritization of Hits Profiling Hits Rational Hit Generation Reducing the Number of False Positive Hits Screening Hit Rates and Yields Screening hit Screening hit rates Screening hits, promiscuous Silico Screening Hit Finding from Database Mining Single-hit kinetics Target hit rate The Hit-to-lead Process True hit Two hit hypothesis Visualization of Library Designs during Hit-to-lead Efforts Word “hits