Zizanoic acid

The reaction was also used by Japanese chemists in a study of the stereochemistry of zizanoic acid. Thus the carboxylic acid (3) was converted into the chloroketone (4) by chlorodecarboxylation. 

Based upon a consideration of a possible biogenetic pathway to the tricyclo-vetivane group of sesquiterpenoids, MacSweeney and Ramage have accomplished a very elegant synthesis of zizanoic acid (384 = C02H,R = H). The... 

Yoshikoshi et al. have published the complete details of the synthesis of epi-zizanoic acid (154). Having developed an efficient route for the construction... 

Helminthosporal i i-Longifolic acid Petasalbine Zizanoic acid Rotunols Furopelargone A Hinokiic acid Confertifolin Drimenin C15H22O3... 

Zearalenone, Y14 Zeaxanthin, T55 Zeylanine, T20 Zingiberene, T2 Zizanin A, T41 Zizanoic acid, T27... 

A new synthesis of (l/J)-frfl/i5-chrysanthemic ester has appeared along with routes to its known chiral precursors. A remarkable illustration of the use of electrocyclizations in the synthesis of endiandric acids is reported which has important biosynthetic consequences. Other notable synthetic achievements this year include ( )-pisiferic acid, (+)-zizanoic acid, ( )-lysergic acid, and chorismic acid. ... 

Kido, F., H. Uda, and A. Yoshikoshi The Structure of Zizanoic Acid, A Novel Sesquiterpene in Vetiver Oil. Tetrahedron Letters 1967, 2815. 

MacSweeney, D. F., and R. Ramage A Stereospecific Total Synthesis of Zizanoic and Isozizanoic Acids. Tetrahedron 27, 1481 (1971). 

---