Zeta potential volume average

Maa and Hsu (75) reported the formation of nano-particles by the double-emulsion method (W/OAV), using methylene chloride as an organic solvent and poly(vinyl alcohol) (PVA) or human serum albumin (HSA) as a surfactant. Experimental parameters such as the preparation temperature, the solvent-evaporation method, the internal aqueous phase volume, the surfactant concentration, and the polymer molecular weight were investigated for particle size, the zeta potential, the residual surfactant percentage, and the poly-dispersity index. Preparation parameters leading to particles with well-defined characteristics such as an average size around 200 nm and a polydispersity index lower than 0.1 were identified. 

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