ZerZ-butyl ethers

ZerZ-Butyl-l-chloro-2-naphthol [525-27-9] M 232.7, m 76 , b 185 /15mm. ether. 

Casanova M, Heck HdA. 1997. Lack of evidence for the involvement of formaldehyde in the hepatocarcinogenicity of methyl ZerZ/ary-butyl ether in CD-I mice. Chem Biol Interact 105 131-143. 

The benzene and unchanged ZerZ.-butyl alcohol are removed by distillation from the steam bath, the final traces being removed under 10-30 mm. pressure. A liter of dry ether is added, and the solid aluminum tert. -butoxide is dissolved by refluxing for a short... 

Ether and ZerZ.-butyl alcohol are removed by distillation at atmospheric pressure without a column, and the xylene is removed by distillation through a 35-cm. Vigreux column at 25-50 mm. The residue is transferred to a smaller flask, and the acetophenone is first distilled at about 80°/10 mm., and finally the dypnone is distilled at 150-155°/ mm. (Notes 7 and 8). The yield is 85-91 g. (77-82 per cent of the theoretical amount) of a yellow liquid. 

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